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Dosing, Administration and Storage

Dosing, Administration and Storage of TAMIFLU

TAMIFLU is available in capsules — in 30mg, 45mg, and 75mg doses — and a liquid form for pediatric and mature patients who may have difficulty swallowing a capsule. ¹

	ADULT DOSING	DOSAGE
	Treatment	75 mg bid for 5 days
	Prophylaxis	75 mg qd for 10 days 1

	RENAL IMPAIRMENT DOSING* (for patients with creatinine clearance between 10 mL/min and 30 mL/min)
	Treatment dosing	75 mg once daily for 5 days
	Prophylaxis dosing	75 mg every other day or 30 mg oral suspension once daily 1

*No recommended dosing regimens are available for patients undergoing routine hemodialysis and continuous peritoneal dialysis treatment with end-stage renal disease.

	PEDIATRIC (1-12 years) DOSING	BODY WEIGHT lbs (kg)	DOSAGE
	Treatment dosing	≤33 lbs (≤15 kg) >33 lbs to 51 lbs (>15 kg to 23 kg) >51 lbs to 88 lbs (>23 kg to 40 kg) >88 lbs (>40 kg)	30 mg/bid/5 days 45 mg/bid/5 days 60 mg/bid/5 days 75 mg/bid/5 days
	Prophylaxis dosing	≤33 lbs (≤15 kg) >33 lbs to 51 lbs (>15 kg to 23 kg) >51 lbs to 88 lbs (>23 kg to 40 kg) >88 lbs (>40 kg)	30 mg/qd/10 days 45 mg/qd/10 days 60 mg/qd/10 days 75 mg/qd/10 days

An oral dosing dispenser with 30 mg, 45 mg, and 60 mg graduations is provided with the oral suspension; the 75 mg dose can be measured using a combination of 30 mg and 45 mg. It is recommended that patients use this dispenser. In the event that the dispenser provided is lost or damaged, another dosing syringe or other device may be used to deliver the following volumes: 2.5 mL (½ tsp) for children ≤15kg, 3.8 mL (¾ tsp) for >15 to 23 kg, 5.0 mL (1 tsp) for >23 to 40 kg, and 6.2 mL (1 ¼ tsp) for >40 kg.

For instructions on preparing TAMIFLU liquid, please read:

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Taking TAMIFLU with Other Medications

TAMIFLU has been shown to have a minimal chance of negatively interacting with other medications. Over-the-counter medications may be prescribed to reduce severity of symptoms while the antiviral action of TAMIFLU takes effect. ¹

The concurrent use of TAMIFLU and live attenuated influenza vaccine (LAIV) intranasal has not been evaluated. However, due to the possibility for interference between these products, LAIV should not be given within 2 weeks before or 48 hours after taking TAMIFLU, unless it is deemed appropriate by your doctor. Trivalent inactivated influenza vaccine can be administered at any time relative to use of TAMIFLU. ¹

How to Store TAMIFLU

TAMIFLU capsules should be stored at room temperature (77°F [25°C]) and kept in a dry place. Refrigerate constituted liquid TAMIFLU at 36° to 46°F (2° to 8°C). Do not freeze. As with all medications, keep out of the reach of children. ¹

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