The Centers for Disease Control and Prevention (CDC) Recommends Antiviral Treatment as an Adjunct to Seasonal Vaccination37
Important Safety Information
Efficacy of Tamiflu in patients who begin treatment after 48 hours of symptoms has not been established.
Tamiflu is not a substitute for early influenza vaccination on an annual basis as recommended by the Centers for Disease Control and Prevention Advisory Committee on Immunization Practices.
There is no evidence for efficacy of Tamiflu in any illness caused by agents other than influenza virus Types A and B.
2011-2012 CDC guidelines recommend antivirals as an important adjunct to vaccines in the control of influenza32
- Influenza antivirals are 70% to 90% effective in preventing influenza and are useful adjuncts to vaccination.
The American Academy of Pediatrics (AAP) recommends prophylaxis with antivirals for33:
- Postexposure prophylaxis for high-risk family members and close contacts of an infected individual.
- Prevention for unvaccinated family members who are likely to have ongoing, close exposure to unvaccinated children at high risk (including infants and toddlers younger than 2 years of age).
Consider offering antiviral prophylaxis to siblings of infected patients. Recommend that family members see their PCP for advice on antiviral prophylaxis.
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