Adult Postexposure Prophylaxis
Limit influenza transmission
Prophylaxis with antiviral medications is recommended for33:
- Postexposure prophylaxis for high risk family members and close contacts of an infected individual.
- Prevention for unvaccinated family members who are likely to have ongoing, close exposure to unvaccinated children at high risk (including infants and toddlers younger than 2 years of age).
Tamiflu is indicated for prophylaxis of influenza in patients 1 year and older.
About the study
A cluster-randomized, double-blind, placebo-controlled study was conducted at 76 centers in North America and Europe during the winter of 1998-1999 and involved 377 index cases — 43% with laboratory-confirmed influenza infection.22
Limitations of Use
The following points should be considered before initiating treatment with Tamiflu:1
Important Safety Information1
Cases of anaphylaxis and serious skin reactions, including toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme, have been reported in postmarketing experience with Tamiflu. Tamiflu should be stopped and appropriate treatment instituted if an allergic-like reaction occurs or is suspected.1
Please see the Tamiflu full Prescribing Information for complete safety information.