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TAMIFLU for Treatment of Influenza

TAMIFLU for Treatment of Influenza

Treatment with TAMIFLU Significantly Reduces the Duration of Influenza

TAMIFLU is indicated for the treatment of uncomplicated acute illness due to influenza infection in patients 1 year and older who have been symptomatic for no more than 2 days. TAMIFLU is indicated for prophylaxis of influenza in patients 1 year and older. TAMIFLU is not a substitute for early and annual influenza vaccination. ¹

Treat Influenza in Adults

TAMIFLU Significantly Reduces Duration of Illness by 1.3 days (30%) Compared with Placebo in Adults 18 to 65 Years Old ⁹

• TAMIFLU significantly reduced flu duration by 1.3 days (30%) versus placebo (P<0.001)⁹
• Symptom relief was defined as the first 24-hour period in which all influenza symptoms were scored as mild or none ⁹

*A randomized, placebo-controlled, double-blind study conducted January through March 1998 that included 629 healthy, non-immunized adults aged 18-65 years. The primary efficacy endpoint was time to resolution of illness, defined as time from study-drug initiation to time of alleviation of symptoms among individuals with influenza infection (374 of the subjects were influenza infected). ⁹

Treat Influenza in Children

TAMIFLU Significantly Reduces Duration of Illness by 1.5 Days (26%) Compared with Placebo in Children 1 to 12 Years Old (P<0.0001) ⁶

• Primary efficacy endpoint was the time to resolution of illness, including mild/absent cough and mild/absent coryza, return to normal activity and euthermia (N=452)⁶
• In children, TAMIFLU reduces median duration of fever by 25 hours ⁶

A randomized, double-blind, placebo-controlled study in which 695 children aged 1 to 12 years with fever ≥100°F (≥38°C) and a history of cough or coryza <48 h duration received oseltamivir 2 mg/kg/dose or placebo twice daily for 5 days. ⁶

TAMIFLU is indicated for the treatment of influenza in patients 1 year and older who have been symptomatic for no more than 2 days.

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